Are you having issues with erections? Is there a cure for ED? Regardless of your age, you’re not the only one experiencing this. Around one-quarter of men under the age of 40 suffer with ED on a regular basis. Fortunately, there are a wide variety of erectile dysfunction drugs on the market that may help you get and keep an erection without difficulty.
Sildenafil (in Viagra® and generic Viagra), vardenafil (in Levitra®), and Tadalafil Vidalista 20 are the three most common erectile dysfunction medications on the market (Cialis). All of these therapies for erectile dysfunction date back to the 1990s and early 2000s, when they were initially brought to the market. Additionally, there is Stendra®, a new generation of erectile dysfunction medicine, which treats erectile dysfunction without as many adverse effects as the first-generation therapies. Cenforce 100,Fildena 100,Vidalista 20 are Commonly used. Experts recommend Generic Villa Pharmacy.
Despite the fact that there is no “ideal” medication for ED, all four erectile dysfunction therapies have the same primary benefit: improved blood flow to the penis and less difficulty in achieving an erection.
But there are certain distinctions, such as shorter or longer half-lives, and differing side effect profiles, between the two.
Viagra and other ED medications
Our comparison of sildenafil, which is the active component in Viagra and is also found in Levitra and Cialis, with tadalin, which is found in Cialis, provides you with a better knowledge of the most often prescribed treatments for erectile dysfunction in today’s world.
Sildenafil (sildenafil citrate) (active ingredient in Viagra)
Viagra’s main component, sildenafil, is one of the most extensively prescribed ED medications on the market today. In the late 1990s, sildenafil was licenced as an ED medicine after being developed as a therapy for heart health concerns. As of 1998, Viagra has been one of the most recommended drugs for ED in the globe.
- Sildenafil’s Mechanism of Action
Increasing blood flow to the penis’ spongy erectile tissue is how Sildenafil works, making erections simpler to attain.
Sildenafil may be taken with or without food, although taking it after a large meal, especially one high in fat, may cause your body to absorb the medication more slowly.
- There are certain side effects of using Sildenafil.
As with most other ED medications, sildenafil may cause headaches, nasal blockage, flushing skin, and heartburn.
It is also possible that Sildenafil may cause more significant adverse effects, especially in those with heart issues or those who are using other prescription erection medications. Additionally, it may interact with nitrates used to treat hypertension and induce low blood pressure. You should see a doctor before using any prescription medication, including sildenafil, for erectile dysfunction.
- Amount of Sildenafil
From 20mg to 100mg, Sildenafil is available in a range of strengths. Higher dosages of sildenafil are often used to treat more severe instances of erectile dysfunction in men who don’t react to the 20 or 50mg pills of the drug. For the most part, sildenafil is popular for a good reason—it works! The drug sildenafil is a safe and effective treatment for erectile dysfunction in the vast majority of men.
The erectile dysfunction drug Tadalafil (active ingredient in Cialis)
In the 1990s, the FDA authorized tadalafil, a longer-lasting, sildenafil-like ED medication, for use in the treatment of erectile dysfunction. Cialis is also known as the drug tadalafil. Tadalafil has a half-life of 17.5 hours, making it the longest-acting erectile dysfunction medicine currently on the market.
In comparison, a normal sildenafil dosage lasts between three and five hours. A single dosage of tadalafil (Cialis) would have the same effects as many sildenafil pills taken over two days.
- Tadalafil’s Mechanism of Action
Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor. Your penis produces nitric oxide when signals reach the corpora cavernosa (the spongy tissue that runs through the shaft of your penis). In the penis, the nitric oxide stimulates the synthesis of cGMP in the smooth muscle, which relaxes those muscles and allows blood to flow into the penis, where it is trapped to generate an erection.
Erectile dysfunction is primarily caused by the degradation of cGMP by PDE5, which occurs over time.
- Some of the side effects of Tadalafil
Facial flushing and a stuffy nose are among the most prevalent adverse effects of Tadalafil compared to sildenafil. Because of its vasodilation impact, tadalafil might induce muscular pains and back discomfort.
As with sildenafil, several drugs intended to treat hypertension or other cardiovascular issues may interact with tadalafil as well. Before using tadalafil, you should tell your doctor if you use any other erection medicine.
The extended half-life of tadalafil over sildenafil is the most important benefit for the majority of individuals. Tadalafil lasts for most of the weekend on a single dosage, so there’s no need to take it just before bed.
- How Much Tadalafil You Need to Take
The normal dose of tadalafil is much lower than that of sildenafil. Starting with a dosage of 10mg, 5mg, and 20mg might be utilised depending on how each individual responds to therapy. For guys who do not want to take an erectile dysfunction medication right before to intercourse and who are looking for a long-lasting pill, tadalafil is a decent choice.
Vardenafil (generic name) (active ingredient in Levitra)
Vardenafil, like sildenafil and tadalafil, is an ED medication that acts in a similar way. Cialis was developed in the early 2000s as a substitute for sildenafil with a longer half-life, making it an effective therapy for Erectile Dysfunction (ED). Levitra is brand name for vardenafil. Vardenafil, like sildenafil and tadalafil, is a prescription drug in most countries, so you’ll need to see a doctor before using it.
- Vardenafil’s Functions
It is a well known PDE5 inhibitor like tadalafil, which blocks the development of the PDE5 enzyme.
Aside from the fact that vardenafil is more powerful than sildenafil, which lasts three to five hours, studies have shown that vardenafil is effective for up to seven hours, after which time it remains active in the body but doesn’t produce as strong an impact.
- Some of the Side Effects of Vardenafil
Vardenafil’s negative effects are comparable to those of other ED medicines. Facial flushing, headaches, a runny nose, and heartburn are among the most often reported adverse effects. These symptoms normally subside over the course of several hours as the medication’s concentration in your system drops.
Also, those with preexisting cardiac issues who are taking other medicines are more likely to have more significant adverse effects from this drug. Vardenafil, like sildenafil, tadalafil, and other ED medicines, may interact with nitrates.
As a result, speaking with a doctor or other medical practitioner is critical before beginning any ED medication, including vardenafil.
- Amount of Vardenafil
Vardenafil has a half-life of around an hour after a standard dosage. Vardenafil, like sildenafil and tadalafil, may be taken either with or without meals, much like those two other drugs. Vardenafil is far more potent than sildenafil milligramme for milligramme, hence it is prescribed at lower doses. Vardenafil’s recommended beginning dosage is 10mg, and the pills come in 2.5, 5, 10 and 20mg strengths.
All-in-all, for guys who want something that lasts longer than sildenafil but don’t require the 36+ hours of therapy provided by Tadalafil, Vardenafil is the best option.